In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...

Nucleotide excision repair is a DNA repair pathway which detects and fixes various DNA lesions that distort the structure of DNA. In bacteria, the pathway starts with the UvrA protein which has two ...

In this Review, we discuss the key types of non-B DNA structure with a focus on their roles in genetic instability and disease aetiology. We begin by highlighting the dynamic nature of non-B DNA ...